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1

Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14α-demethylase (CYP51)

Tina Korošec, Jure Ačimovič, Matej Seliškar, Darko Kocjan, Klementina Fon Tacer, Damjana Rozman, Uroš Urleb

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 438 KB

english, 2008

2

Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells

Jure Acimovic, Anita Lövgren-Sandblom, Katalin Monostory, Damjana Rozman, Marko Golicnik, Dieter Lutjohann, Ingemar Björkhem

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 372 KB

english, 2009

3

Determination of reference genes for circadian studies in different tissues and mouse strains

Rok Kosir, Jure Acimovic, Marko Golicnik, Martina Perse, Gregor Majdic, Martina Fink, Damjana Rozman

Journal:

BMC Molecular Biology

Year:

2010

Language:

english

File:

PDF, 738 KB

english, 2010

4

Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland – involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1

Rok Košir, Ursula Prosenc Zmrzljak, Tanja Bele, Jure Acimovic, Martina Perse, Gregor Majdic, Cornelia Prehn, Jerzy Adamski, Damjana Rozman

Journal:

Year:

2012

Language:

english

File:

PDF, 632 KB

english, 2012

5

CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver

Jure Acimovic, Martina Fink, Denis Pompon, Ingemar Bjorkhem, Jun Hirayama, Paolo Sassone-Corsi, Marko Golicnik, Damjana Rozman

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 393 KB

english, 2008

6

Circadian rhythm of cholesterol synthesis in mouse liver: A statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice

Jure Ačimovič, Rok Košir, Damijana Kastelec, Martina Perše, Gregor Majdič, Damjana Rozman, Katarina Košmelj, Marko Goličnik

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

7

The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone

Jure Acimovic, Anita Lövgren-Sandblom, Lennart C. Eriksson, Linda Björkhem-Bergman

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 352 KB

english, 2012

8

Analysis of the steady-state relations and control-algorithm characterisation in a mathematical model of cholesterol biosynthesis

Belič, Aleš, Ačimovič, Jure, Naik, Adviti, Goličnik, Marko

Journal:

Simulation Modelling Practice and Theory

Year:

2013

Language:

english

File:

PDF, 294 KB

english, 2013

9

Cholesterogenic Lanosterol 14α-Demethylase ( CYP51 ) Is an Immediate Early Response Gene

Fink, Martina, Ačimovič, Jure, Režen, Tadeja, Tanšek, Nataša, Rozman, Damjana

Journal:

Year:

2005

Language:

english

File:

PDF, 394 KB

english, 2005

10

Statin-induced Myopathy and Ubiquinone Levels in Serum - Results from a Prospective, Observational Study

Skilving, Ilona, Acimovic, Jure, Rane, Anders, Ovesjö, Marie-Louise, Björkhem-Bergman, Linda

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2015

Language:

english

File:

PDF, 84 KB

english, 2015

11

Mouse genotypes drive the liver and adrenal gland clocks

Košir, Rok, Prosenc Zmrzljak, Uršula, Korenčič, Anja, Juvan, Peter, Ačimovič, Jure, Rozman, Damjana

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.81 MB

english, 2016

12

Cytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis

Ačimovič, Jure, Goyal, Sandeep, Košir, Rok, Goličnik, Marko, Perše, Martina, Belič, Ales, Urlep, Žiga, Guengerich, F. Peter, Rozman, Damjana

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

13

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective

Cvijovic, Marija, Höfer, Thomas, Aćimović, Jure, Alberghina, Lilia, Almaas, Eivind, Besozzi, Daniela, Blomberg, Anders, Bretschneider, Till, Cascante, Marta, Collin, Olivier, de Atauri, Pedro, Depner,

Journal:

npj Systems Biology and Applications

Year:

2016

Language:

english

File:

PDF, 364 KB

english, 2016

14

Sulphatation Does Not Appear to Be a Protective Mechanism to Prevent Oxysterol Accumulation in Humans and Mice

Acimovic, Jure, Lövgren-Sandblom, Anita, Olin, Maria, Ali, Zeina, Heverin, Maura, Schüle, Rebecca, Schöls, Ludger, Fischler, Björn, Fickert, Peter, Trauner, Michael, Björkhem, Ingemar, Lobaccaro, Jean

Journal:

Year:

2013

Language:

english

File:

PDF, 106 KB

english, 2013

15

Cholesterol, Oxysterol, Triglyceride, and Coenzyme Q Homeostasis in ALS. Evidence against the Hypothesis That Elevated 27-Hydroxycholesterol Is a Pathogenic Factor

Wuolikainen, Anna, Acimovic, Jure, Lövgren-Sandblom, Anita, Parini, Paolo, Andersen, Peter M., Björkhem, Ingemar, Cai, Huaibin

Journal:

Year:

2014

Language:

english

File:

PDF, 957 KB

english, 2014

16

Steroidal Triterpenes of Cholesterol Synthesis

Ačimovič, Jure, Rozman, Damjana

Journal:

Year:

2013

Language:

english

File:

PDF, 275 KB

english, 2013